Historical personalities
- Hemu Kalani, Freedom Fighter
- Hazrat Khawaja Muhammad Zaman of Luari Sharif
- Shah Abdul Latif Bhittai
- Shah Inayat Shaheed
- Lal Shahbaz Qalander
- Sachal Sarmast
- Dodo Bin Khafef Soomro III
- Jam Nizamuddin II
- Jam Feroz
- Jam Unar
- Jam Tamachi
- Abu'l-Fazl ibn Mubarak
- Mir Ahmed Nasrallah Thattvi
- Mir Ali Sir Thattvi
- Mirza Ghazi Beg
- Muhammad Salih Tahtawi
- Mian Adam Shah Kalhoro, Amir
- Main Noor Mohammad Kalhoro, Ruler of Sindh
- Muhammad Muradyab Khan (Nawab Sarbuland Khan), Ruler of Sindh
- Mian Ghuam Shah Kalhoro (Shah Wardi Khan), Ruler of Sindh
- Mir Nasir Khan Talpur
- Mir Sher Muhammad Talpur
- Gernal Hosh Mohammad Sheedi
- Mir Ali Murad Talpur
- Mir Allahyar Talpur
- Hoshu Sheedi
- Muhammad Ali Jinnah
- Fatima Jinnah
- Sibghatullah Shah Rashidi
- Ubaidullah Sindhi
- Ghulam Mustafa Khan
- Sardar Darya Khan
- Raja Dahir
- Sinbad the Sailor, a mythical figure who may have originated in Sindh
Politics
- Syed Shah Mardan Shah-II
- Rasool Bux Palijo
- G.M Syed
- Lal Krishna Advani, Leader of BJP and former Deputy Prime Minister and Home Minister of India
- Zulfikar Ali Bhutto
- Benazir Bhutto
- Ayaz Latif Palijo
- Bashir Qureshi
- Mohammad Khan Junejo
- Sir Shah Nawaz Bhutto
- Ghulam Hussain Hidayatullah
- Asif Zardari
- Ghulam Mustafa Jatoi
- Mumtaz Ali Bhutto
- Haider Bux Jatoi founder of 'Jeay Sindh' slogan
- Elahi Bux Soomro, former Parliamentary Speaker
- Yusuf Haroon
- Murtaza Bhutto
- Haji Amir Bux Junejo
- Muhammad Mian Soomro
- Fatima Bhutto,author
- Sucheta Kriplani, first Sindhi Indian Woman Chief Minister
- Lal Krishna Advani
- K. R. Malkani
- Mir Ghalib Hussain Domki
- Allah Bux Soomro, first Prime Minister of Sindh
- Mohammad Ali Jinnah Founder of Pakistan
- Syed Zafar Ali Shah Former Deputy Speaker Of Pakistan.
Journalists
Artists and painters
Poets
- Talib-ul-Mola
- Shah Abdul Latif Bhitai
- Sachal Sarmast
- Anwar Pirzada, Sindhi poet, journalist
- Shaikh Ayaz, Sindhi/Urdu poet, scholar
- Qadir Bux Bedil
- Imdad Hussaini
- Elsa Kazi
- Pir Sadardin
- Tajal Bewas
- Minyoon Shah Inat
- Shah Abdul Karim Bulri
- Shah Inayatullah
- Minyoon Shah Inat
- Sami
- Rohal Faqir
- Bedil
- Muhammad Mohsin Bekas
- Darya Khan Rind
- Sikandar Khan Khoso
- Sawan Fakir
- Adal Soomro
- Allah Baksh Sarshar Uqaili
- Anwar Peerzada
- Ameer Bukhari
- Shah Inayat Rizvi
- Elsa Kazi
- Ghulam Ali Allana
- Syed Ahmed Bukhari, known by his pen name "Ustad Bukhari"
Short story writers
Science and technology
- Sind ibn Ali, Sindhi Muslim astronomer, translator, mathematician and engineer
- Ahmed Mohiuddin
- Gul Agha, computer scientist
- Pervez Hoodbhoy
- Raziuddin Siddiqui
- Abdul-Majid Bhurgri - The founder of computing in Sindhi
- Rajeev Motwani - Co-author of PageRank
Educationalists
- Hassan Ali Effendi
- Allama I. I. Kazi
- Ghulam Mustafa Khan
- Hassanally A. Rahman
- Nabi Bux Khan Baloch
- Haji Mehar Ali Khoja
- Khan Bahadur Ghulam Nabi Kazi, first DPI Sindh 1936-39
- Abul Khair Kashfi
- Abul Lais Siddiqui
- Aslam Farrukhi
- Farman Fatehpuri
- Ghulam Mustafa Khan
- Jameel Jalibi
- Khalida Ghous
- Moonis Ahmar
- Naseem Amrohvi
- Talat A. Wizarat
- Muhammad Ibrahim Joyo
- Umar Bin Muhammad Daudpota
- Ali Ahmed S Kazi
- Justice Mushtak Ali Kazi
- Dr. Mutawakkil Kazi Judge of the High Court of Sindh
- Aftab Ghulam Nabi Kazi 8h Governor of the State Bank of Pakistan
- Khan Bahadur Ghulam Nabi Kazi
- Ahmed Hussain A. Kazi
- Ahmed Hussain A. Kazi
Entertainment industry
- Abida Parveen, Pakistani singer of Sindhi descent
- G P Sippy, filmmaker from India
- Ramesh Sippy, Indian director, son of G P Sippy
- Ramsay Brothers, Horror Filmmakers from India
- Govind Nihalani, director of serious and art films
- Sangeeta Bijlani, Indian Actress
- Babita, Indian actress and mother of Kareena and Karishma Kapoor
- Sadhna, Indian Actress
- Asrani, Famous Indian Comedian/Actor
- Aftab Shivdasani, Indian actor
- Hiten Tejwani, television actor
- Vashu Bhagnani, Indian filmmaker
- Rajkumar Hirani, Indian movie director
- Dalip Tahil, Indian actor
- Vishal Dadlani, Indian music director
- Ritesh Sidhwani, Indian movie producer
- Tarun Mansukhani, Indian movie director
- Ranveer Singh, Indian actor
- Nikhil Advani, Indian director and screenwriter
- Fahad Mustafa, Pakistani actor, producer, host, anchor and model
- Sanam Baloch, Pakistani actress and a television host
- Mustafa Qureshi, film and television actor from Sindh, Pakistan
- Shafi Muhammad Shah, Pakistani film and television actor
- Hansika Motwani, Indian actress
- Sarmad Sindhi, Sindhi singer from Sindh (Beejal of Sindh)
- Muhammad Juman, Sindhi musician and classical singer
- Zarina Baloch, Pakistani folk music singer and composer
- Fahad Mustafa, Pakistani actor, producer, host, anchor and model
- Sanam Saeed, British Pakistani actress, singer and model
Law experts
Scholars
- Allama Makhdoom Muhammad Hashim Thattvi
- Mukhdoom Muhammad Hayat Bhatti
- Ghulam Mustafa Khan, scholar of Islam and the Quran, linguist, professor of Urdu
- Hassam-ud-Din Rashidi
- Umar Bin Muhammad Daudpota
- Mirza Qalich Baig
- Allama I. I. Kazi
- Nabi Bux Khan Baloch
- Elsa Kazi
- Ali Muhammad Rashidi
- Muhammad Ibrahim Joyo
- Ghulam Ali Allana
- Maulana Ubaidullah Sindhi
- M. H. Panhwar
Researchers
- Ghulam Mustafa Khan, researcher, linguist, poet, author, scholar
- Fahmida Hussain
- Anwar Peerzada
Writers
- Muhammad Ibrahim Joyo
- Imdad Ali Imam Ali Kazi
- Mirza Kalich Beg
- Ghulam Nabi "Gul" Wajahat Publication Larkana
- Nabi Bux Khan Baloch
- Shaikh Ayaz
- Sobho Gianchandani writer
- Jamal Abro, Sindhi novelist
- Fehmida Riaz, writer, poet, activist
- Ghulam Mustafa Khan, writer, critic, linguist, researcher, scholar
- Muzaffar Warsi, poet
- Zamir Ali Badayuni, critic
- Altaf Shaikh
- Naseem Kharal
- Mir Muhammad Soomro, religious scholar, historian, biographer, poet
- Faqeer Muhammad Soomro, Writer, Researcher & Columnist. Writer of "Soomran Jo Shujro"
- Altaf Malkani
Business and industry
- Sabir Bhatia, Indian entrepreneur and founder of Hotmail
- Yusuf Haroon
- Mahmoud Haroon
- Agha Hasan Abedi, banker
- Hinduja Brothers, Hinduja Group
- Micky Jagtiani
- Eros International
- Tips Industries Limited
- Hari Harilela
- Rajan Raheja
Philanthropists and social activists
Economics
- Dr. Shamshad Akhtar
- Hameed Haroon
- Abdul Hafeez Shaikh, Finance Minister of Pakistan
- Naveed Qamar, Finance Minister of Pakistan
- Akhtar Hameed Khan, pioneer of microcredit and microfinance in Pakistan, founder of Orangi Pilot Project
Law and judiciary
Metaphysics, spirituality and religion
- Ghulam Mustafa Khan, Head of Naqashbandi Sufi Order, scholar, writer, poet
- Abu Mashar Sindhi (786 AD), teacher of Arab scholars
- Abu Raja Sindhi (d. 321 A.H.), scholar, poet, teacher
- Abul Hassan Sindhi (d. 1176 AH), made the first translation of Qur'an from Arabic to Sindhi
- Allama Makhdoom Muhammad Hashim Thattvi (died 1174 AH), Ahl-us-Sunnah scholar
- Maulana Taj Mohammad Amrothi (d. 1929), freedom fighter from Sukkur, Sindh
- Abu'l-Fazl ibn Mubarak, vizier of the Mughal emperor Akbar and author of the Akbarnama
- Mir Ahmed Nasrallah Thattvi, Muslim scholar at the court of Mughal Emperor Akbar
- Mir Ali Sir Thattvi, Sindhi Muslim historian born after the rule of Mughal EmperorAurangzeb
- Tahir Muhammad Thattvi, Sindhi Muslim poet and historian during the rule of the Mughal Empire
- Abu'l-Qásim Faizi, a Persian poet of late medieval India
- Allama Muhammad Idrees Dahiri, Islamic scholar, preacher, writer, author, poet and researcher
- Hafiz Muhammad Siddique, a scholar from Sindh and founder of school of thought in Bharchundi
- Ubaidullah Sindhi, a pan-Islamic leader and a political activist
- Mohammad Hayya Al-Sindhi, a prominent Muslim scholar in Medina in the 18th century
- Raees-Ul-Muhajireen Barrister Jan Muhammad Junejo a leader of the Khilafat Movement
- Badi' ud-Din Shah al-Rashidi
- Hazrat Khwaja Muhammad Tahir
- Allama Ali Khan Abro
- Maulana deen Muhammad Wafai
- Moulana Jan Mohammad Abbasi
- Makhdoom Bilawal
- Asadullah Bhutto
- Sibghatullah Shah Rashidi, spiritual leader of the Hurs
- Syed Shah Mardan Shah-II, spiritual leader of Hurs
Saints and sufis
Sports
- Syed Hussain Shah, boxer who won the bronze medal for boxing at the 1988 Summer Olympics
- Pankaj Advani, world champion in Snooker and Billiards from India
- Abdul Rashid Qambrani, boxer
- Narendra Hirwani, Cricketer from India
- Isha Lakhani, is an former Indian tennis player. She has been a member of the India Fed Cup team.
Medicine
- Mir Masoom Bakhree
- Abdul Hai Arifi, Doctor of Homeopathic Medicine
Oye the Forget me Hmmmm Ok i will add my name by myself
And the most talented gorgues Amazing beyond Perfection the Best and One n Only
Rabiya Dahahar
